Add a taint to one of the nodes of the Kubernetes cluster. For the specific microservice, configure a pod anti-affinity label that has the name of the tainted node as a value.

Use Istio's fault injection on the particular microservice whose faulty behavior you want to simulate.

Destroy one of the nodes of the Kubernetes cluster to observe the behavior.

Configure Istio's traffic management features to steer the traffic away from a crashing microservice.