An AWS Region is a physical location around the world where AWS clusters multiple data centers. These data centers are known as Availability Zones and are designed to be isolated from each other within the same region to provide fault tolerance, scalability, and high availability for AWS services and resources. Customers can select the most suitable Region for their resources based on compliance requirements, latency, and data residency concerns. The correct answer is B, as it accurately describes the concept of an AWS Region.