The correct answer is C, which states that 'Availability Zones contain multiple data centers.' This is accurate as an Availability Zone (AZ) in AWS is designed to be a physical location within an AWS Region that is isolated from other Availability Zones. It typically consists of one or more discrete data centers, each with redundant power, networking, and connectivity, to ensure high availability and fault tolerance for applications. The other options are incorrect because: A) Edge locations are not defined by containing AWS Regions; B) AWS Regions do not contain multiple Regional edge caches; and D) Each data center does not contain multiple edge locations, as edge locations are distributed globally to provide content delivery and cloud services closer to end-users.