To ensure high availability and low latency for Cloud Run services, deploying across multiple regions is essential as it mitigates regional outages. A global HTTPS load balancer with serverless Network Endpoint Groups (NEGs) is the correct approach because serverless NEGs allow the load balancer to route traffic to Cloud Run services, and the global HTTPS load balancer optimizes traffic distribution based on proximity and health checks. Option B correctly combines multi-region deployment, serverless NEGs, and a global HTTPS load balancer. Other options are incorrect: options A and C reference availability zones (Cloud Run abstracts zone management) or improper components (TCP load balancer, Cloud Endpoints), and option D uses DNS round-robin, which lacks intelligent routing and health checks.